With your doctor’s approval, consider trying the following. Scientists have identified several lifestyle changes that could enhance your gut health and help keep bipolar symptoms in check. This makes it harder for researchers to find out whether bipolar disorder itself, a coexisting mental health condition, or a combination of the two are influencing the gut microbiome, Day explains. What’s more, people with bipolar disorder often have additional mental health conditions, such as psychosis and anxiety disorders. “And so, the next question is whether modulating the microbiome to meet health-associated patterns might predict or result in positive clinical outcomes.”Īnd while preliminary research has addressed the gut microbiome’s relationship with bipolar disorder overall, experts do not yet know if microbiome issues vary by the type of bipolar disorder an individual has - bipolar 1, bipolar 2, cyclothymia, or other specified and unspecified bipolar and related disorders. “There is currently no consensus about what a ‘healthy’ microbiome even is,” Day notes. Kellman, who was not affiliated with the study. “ Further, reduced levels of this particular beneficial bacteria were associated with more severe bipolar symptoms,” says Dr. Specifically, people with bipolar disorder may have decreased levels Faecalibacterium, one of the most important kinds of bacteria in the human gut microbiome, according to a small study published in the April 2017 Journal of Psychiatric Research. Bipolar Disorder and the Gut Microbiome: What Research Has Revealed So FarĪ systematic review and meta-analysis published in the August 2016 issue of Medicine found that people with IBS were twice as likely to have bipolar disorder than people without IBS.Īnd while everyone’s gut composition is unique, people with mental health conditions like bipolar disorder appear to have fewer healthy microorganisms and more unhealthy ones in their stomach and intestines.
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Īlthough scientific research on the gut microbiome–bipolar disorder connection is still new, researchers have already made some fascinating discoveries about how the two influence each other. Scientists are studying this relationship in part because it could lead to other treatments for bipolar disorder, alongside standard therapies like medication, to help improve the lives of people with this condition, according to the authors of the previously mentioned review in the International Journal of Molecular Sciences. “ Many patients with bipolar disorder have gastrointestinal illnesses such as irritable bowel syndrome (IBS), and research suggests this may be linked to dysfunction within the gut microbiome,” says Raphael Kellman, MD, an integrative and functional medicine physician at Kellman Wellness Center in New York City, and author of The Microbiome Diet.
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For example, a review published in February 2020 in the journal Neuropsychobiology found that people with bipolar disorder tend to have differences in the composition of their microbiome and more gastrointestinal illnesses than people without the disorder. Ongoing research indicates a connection between the gut microbiome and several mental health conditions, including bipolar disorder.
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Day has conducted research related to the gut microbiome. “We are learning that other physiological systems can be affected by what’s happening inside the gut, and this includes what happens in the brain,” says Richard Day, MBBS, the vice president of medical affairs and clinical development at ADM Protexin, a company that produces probiotic and live bacteria health products. Given how closely the gut and brain interact, it’s not surprising that the bacteria in the gut could have a direct effect on brain functions like mood and behavior.
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But did you know that those bacteria are not only good for your gut, but for your mental health, too?Īll hail the gut-brain-microbiota axis, a network through which the gut and the brain constantly exchange information, according to a review published in April 2021 in the International Journal of Molecular Sciences. You may be familiar with the gut microbiome - the trillions of beneficial bacteria and other microorganisms in your digestive tract that support your overall health.